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WHAT IS MACULAR DEGENERATION?

Macular degeneration is the leading cause of blindness
affecting more Americans
than cataracts and glaucoma combined.

Few people are aware that macular degeneration is an incurable eye disease and that it is the leading cause of blindness for those aged 55 and older in the United States, affecting more than 10 million Americans.

Macular degeneration is caused by the deterioration of the central portion of the retina, the inside back layer of the eye that records the images we see and sends them via the optic nerve from the eye to the brain. The retina's central portion, known as the macula, is responsible for focusing central vision in the eye, and it controls our ability to read, drive a car, recognize faces or colors, and see objects in fine detail.

As people age, their chances for developing eye diseases increase dramatically. Unfortunately, the specific factors that cause macular degeneration are not conclusively known and research into this little-understood disease is limited by insufficient funding.

The Complement System - An Interview with Gregory Hageman, PhD

Wavy Macular Degeneration

The former Director of the National Eye Institute, National Institutes of Health, has stated that macular degeneration will soon take on aspects of an epidemic.

According to a recent poll, Americans dread blindness more than any other disability. Recent studies indicate that by the year 2025, the population of people over the age of 65 in the United States will be six times higher than in 1990. "As 'baby boomers' age and a higher percentage of Americans reach age 60, AMD will become an even more serious medical issue," said Dr Carl Kupfer, [former] director of the National Eye Institute, National Institutes of Health.

"The prevalence of AMD is expected to rise to 6.3 million by the year 2030, when even greater percentages of our population will have turned 60."(1.) In January 1997, Dr Carl Kupfer stated publicly that macular degeneration will soon take on aspects of an epidemic.

For demographics in the United States, please see;

The AMDF Web site will help our readers to better understand macular degeneration. To understand macular degeneration, you should have a basic knowledge of the anatomy of a normal human eye.

For an animation showing the loss of central vision from macular degeneration, click here. (This video presentation requires Quicktime.)

There are two basic types of macular degeneration: "dry" and "wet." Approximately 85% to 90% of the cases of macular degeneration are the "dry" (atrophic) type. Approximately 10-15% of the cases of macular degeneration are the "wet" (exudative) type.

AMDF DVD Hope & Cope - Living with Macular Degeneration

References

1. Recruitment Begins for Study on Age-Related Macular Degeneration, NIH News Wednesday, July 7, 1999.

Medical Disclaimer

Information contained within this Web site is intended solely for educational purposes and is neither intended nor implied to be a substitute for professional medical advice relative to your specific medical condition or question. Always seek the advice of your physician or other health care provider for any questions you may have regarding your medical condition. Only your physician can provide specific diagnoses and therapies. By using this Web site, you agree to this Medical Disclaimer.

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The overall prevalence of neovascular AMD and/or geographic atrophy in the US population 40 years and older is estimated to be 1.47% (95% confidence interval, 1.38%-1.55%), with 1.75 million citizens having AMD. The prevalence of AMD increased dramatically with age, with more than 15% of the white women older than 80 years having neovascular AMD and/or geographic atrophy. Owing to the rapidly aging population, the number of persons having AMD will increase by 50% to 2.95 million in 2020. Age-related macular degeneration affects more than 1.75 million individuals in the United States. Owing to the rapid aging of the US population, this number will increase to almost 3 million by 2020. Citations and Abstracts from April 2004 Archives of Ophthalmology Prevalence of Age-Related Macular Degeneration in the United States The Eye Diseases Prevalence Research Group Archives of Ophthalmology 2004; 122:564-572